Basic Biochemistry Course (CHE 330)

 

Spring 2001 Course  

This course brought special challenges to the integration of molecular visualization into the biochemistry curriculum.  There were 50 students in this course and providing hands-on use of visualization software can be difficult. Therefore, the Protein Exploration Project was initiated!!

PROTEIN EXPLORATION PROJECT

Approach:  The students were divided up into teams of 3-4 people and they utilized the Science Resource Center to access the online version of Protein Explorer.  The use of Blackboard software made communication with the student teams quite easy. The instructor sent a protein assignment (PDB code or name) via E-mail to the groups.  The teams loaded the proteins into Protein Explorer and searched for noncovalent interactions in the protein systems.  The teams replied to the instructor with their results (type of noncovalent interaction, residues involved, etc.) through E-mail or the digital drop box (in Blackboard).  A sample of the interactions observed by the students can be accessed below.  At this point, these pages are not chime-based.  They show images of noncovalent interactions discovered by the student teams.  The images were generated in RasMol.
  

Ionic Interactions

Cation-p Interactions

Protein-Lipid Interactions

 

MORE to come......

 

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This site was created by Ricky Cox in the Department of Chemistry
Last Modified:  June 25, 2001